The polar oxy-metabolome reveals the 4-hydroxymandelate CoQ10 synthesis pathway

The polar oxy-metabolome reveals the 4-hydroxymandelate CoQ10 synthesis pathway

Nature, Published online: 01 September 2021; doi:10.1038/s41586-021-03865-w

18O2 labelling is used to identify metabolites in human cells that incorporate gaseous oxygen, including 4-hydroxymandelate, an intermediate in the synthesis of the coenzyme Q10 head group.
Source: Nature