Structures of the HER2–HER3–NRG1β complex reveal a dynamic dimer interface

Structures of the HER2–HER3–NRG1β complex reveal a dynamic dimer interface

Nature, Published online: 10 November 2021; doi:10.1038/s41586-021-04084-z

Cryo-electron microscopy structures of the HER2–HER3–NRG1β complex reveal a dynamic HER2–HER3 interface and explain the mechanism for the activating HER2 cancer mutations.
Source: Nature