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Structure and inhibition mechanism of the human citrate transporter NaCT
February 17, 2021
David B Sauer

Structure and inhibition mechanism of the human citrate transporter NaCT

Nature, Published online: 17 February 2021; doi:10.1038/s41586-021-03230-x

Structures of the human sodium-dependent citrate transporter NaCT in complexes with citrate or a small-molecule inhibitor reveal how the inhibitor—which binds to the same site as citrate—arrests the transport cycle of NaCT.Structure and inhibition mechanism of the human citrate transporter NaCT
Source: Nature