Spo11 generates gaps through concerted cuts at sites of topological stress

Spo11 generates gaps through concerted cuts at sites of topological stress

Nature, Published online: 09 June 2021; doi:10.1038/s41586-021-03632-x

Meiotic recombination in yeast is not only initiated by single break sites, but also caused by closely spaced Spo11-dependent double-stranded DNA breaks that create chromosomal gaps.Spo11 generates gaps through concerted cuts at sites of topological stress
Source: Nature