Progressive Cactus is a multiple-genome aligner for the thousand-genome era

Progressive Cactus is a multiple-genome aligner for the thousand-genome era

Nature, Published online: 11 November 2020; doi:10.1038/s41586-020-2871-y

The Progressive Cactus program can create reference-free alignments of hundreds of large vertebrate genomes efficiently, and is used for the alignment of more than 600 amniote genomes.
Source: Nature