Physiological blood–brain transport is impaired with age by a shift in transcytosis

Physiological blood–brain transport is impaired with age by a shift in transcytosis

Nature, Published online: 01 July 2020; doi:10.1038/s41586-020-2453-z

Tagging and tracking the blood plasma proteome as a discovery tool reveals widespread endogenous transport of proteins into the healthy brain and the pharmacologically modifiable mechanisms by which the brain endothelium regulates this process with age.
Source: Nature