NOTUM from <i>Apc</i>-mutant cells biases clonal competition to initiate cancer

NOTUM from <i>Apc</i>-mutant cells biases clonal competition to initiate cancer

Nature, Published online: 02 June 2021; doi:10.1038/s41586-021-03525-z

NOTUM from Apc-mutant cells acts as a key mediator during the early stages of mutation fixation and drives the formation of intestinal adenomas.NOTUM from <i>Apc</i>-mutant cells biases clonal competition to initiate cancer
Source: Nature