Molecular architecture of the human 17S U2 snRNP

Molecular architecture of the human 17S U2 snRNP

Nature, Published online: 03 June 2020; doi:10.1038/s41586-020-2344-3

The cryo-EM structure of human U2 small nuclear ribonucleoprotein (snRNP) offers insights into what rearrangements are required for this snRNP to be stably incorporated into the spliceosome, and the role that the DEAD-box ATPase PRP5 may have in these rearrangements.
Source: Nature

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