Loop extrusion as a mechanism for formation of DNA damage repair foci

Loop extrusion as a mechanism for formation of DNA damage repair foci

Nature, Published online: 17 February 2021; doi:10.1038/s41586-021-03193-z

During the repair of double-stranded DNA breaks, cohesin mediates the extrusion of loops of DNA along which phosphorylated H2AX spreads to establish a repair zone.Loop extrusion as a mechanism for formation of DNA damage repair foci
Source: Nature