In-cell architecture of the nuclear pore and snapshots of its turnover

In-cell architecture of the nuclear pore and snapshots of its turnover

Nature, Published online: 02 September 2020; doi:10.1038/s41586-020-2670-5

In-cell structural studies in Saccharomyces cerevisiae reveal that the configuration of the Nup159 complex is a key determinant of the mRNA export function of the nuclear pore complex, and suggest a model in which nuclear pore complexes are degraded via the autophagy machinery.
Source: Nature