Gene regulation by gonadal hormone receptors underlies brain sex differences

Gene regulation by gonadal hormone receptors underlies brain sex differences

Nature, Published online: 04 May 2022; doi:10.1038/s41586-022-04686-1

A study maps neuronal genomic targets of oestrogen receptor-α and shows how they coordinate brain sexual differentiation, concluding that the genome remains responsive to hormonal changes after structural dimorphisms have been established.
Source: Nature