Fundamental immune–oncogenicity trade-offs define driver mutation fitness

Fundamental immune–oncogenicity trade-offs define driver mutation fitness

Nature, Published online: 11 May 2022; doi:10.1038/s41586-022-04696-z

A mathematical framework to estimate the fitness of cancer driver mutations by integrating mutational bias, oncogenicity and immunogenicity finds fundamental trade-offs in cancer evolution.
Source: Nature