CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity

CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity

Nature, Published online: 18 November 2021; doi:10.1038/s41586-021-04109-7

CRISPR screening and protein–protein interaction networks identify components and mechanisms of nutrient-dependent mTORC1 signalling in regulatory T cells and reveal how mTORC1 integrates immunological cues and nutrient signals for adaptive immunity.
Source: Nature